Upstate South Carolina Vacation Packages 2026 from $741

Upstate South Carolina flight + hotel vacation packages

Price found within the past 48 hours. Click for updated prices.

Hotel Hartness

$741

per person

Oct 22 - Oct 26

found 1 day ago

Roundtrip non-stop flight included

Minneapolis (MSP) to Greenville (GSP)

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and perks like free self parking. There's a bar/lounge on site, and concierge services and wedding services are also provided.

The Windsor Boutique Hotel

Downtown Asheville

Save 100% on your flight

$1,379

per person

Oct 4 - Oct 10

found 5 hours ago

Roundtrip flight included

New York (LGA) to Asheville (AVL)

This hotel features a bar/lounge, free WiFi in public areas, and a snack bar/deli. If you want to take your pet along, this pet-friendly property offers everything you'll need for your pet including food and water bowls. Luggage storage, laundry facilities, and concierge services are also on offer.

AutoCamp Asheville

Save 100% on your flight

$933

per person

Oct 4 - Oct 10

found 5 hours ago

Roundtrip flight included

New York (LGA) to Asheville (AVL)

A restaurant and a bar/lounge are featured at this hotel. Guests will appreciate free perks like free self parking and WiFi in public areas. A coffee shop, a snack bar/deli, and a grocery/convenience store are also on offer.

Grand Bohemian Lodge Asheville, Autograph Collection®

Biltmore Village

Save 100% on your flight

$1,506

per person

Oct 4 - Oct 10

found 5 hours ago

Roundtrip flight included

New York (LGA) to Asheville (AVL)

A full-service spa, a 24-hour gym, and a restaurant are all featured at this luxury hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. There's a bar/lounge on site, and a 24-hour front desk and laundry facilities are also provided.

The Omni Grove Park Inn & Spa

Grove Park- Sunset

Save 100% on your flight

$1,766

per person

Oct 4 - Oct 10

found 5 hours ago

Roundtrip flight included

New York (LGA) to Asheville (AVL)

This luxury resort features a golf course, a full-service spa, and 4 restaurants. Families will appreciate kid-friendly dining and babysitting, along with mountain biking. Enjoy a meal in one of the 2 coffee shops/cafes and perks like free WiFi.

Top Upstate South Carolina hotels deals

Hyatt Regency Greenville

220 N Main St Greenville SC

Free Cancellation

Reserve now, pay when you stay

$157 nightly

$172 total

Aug 9 - Aug 10

Total with taxes and fees

This smoke-free hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. There's a seasonal outdoor pool on site, and concierge services and wedding services are also offered.

Pool

Pet friendly

Grand Bohemian Lodge Greenville, Autograph Collection

44 EAST CAMPERDOWN WAY Greenville SC

Free Cancellation

Reserve now, pay when you stay

$361 nightly

$396 total

Aug 18 - Aug 19

Total with taxes and fees

A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, free WiFi in public areas, and valet parking. A lobby fireplace, a communal living room, and dry cleaning are also on offer.

Spa

Pet friendly

Best Western Plus Clemson Hotel & Conference Center

1310 Tiger Blvd Clemson SC

Free Cancellation

Reserve now, pay when you stay

$110 nightly

$122 total

Jul 31 - Aug 1

Total with taxes and fees

This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. Free self parking, a grocery/convenience store, and express check-out are also offered.

Best Western Plus Greenville I-385 Inn & Suites

831 Congaree Rd Greenville SC

Free Cancellation

Reserve now, pay when you stay

$94 nightly

$103 total

Aug 2 - Aug 3

Total with taxes and fees

This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will appreciate freebies like continental breakfast and free self parking.

Hyatt Place Greenville Downtown

128 East Broad Street Greenville SC

$139 nightly

$153 total

Aug 9 - Aug 10

Total with taxes and fees

This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, and valet parking. Enjoy the 24-hour gym and free buffet breakfast each morning.

Hyatt Place Greenville/Haywood

40 W Orchard Park Dr Greenville SC

Free Cancellation

Reserve now, pay when you stay

$85 nightly

$94 total

Aug 3 - Aug 4

Total with taxes and fees

This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the seasonal outdoor pool and free perks like buffet breakfast and free self parking.

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)

Walk around the campus of Clemson University, a top university in Clemson. Experience the area's theater scene or attend a football game.

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Frequently asked questions

How much are vacation packages to Upstate South Carolina?

Travelocity offers great package deals to Upstate South Carolina, including hotels and flights, starting from as low as $741. With all the cash you save, you could throw in some cool tours or possibly even add a couple of extra days to your exciting adventure.

Where can I get the best vacation package deals for Upstate South Carolina?

There are sensational Upstate South Carolina package deals to be snapped up with Travelocity. Did you know we partner with as many as 400 airlines and 1,000,000 properties around the world? Keep that in mind the next time you're ready to check another place off your must-visit list.

Why should I purchase my Upstate South Carolina vacation package with Travelocity?

Whether you're on the hunt for the ultimate unplugged vacation or you crave the fun and excitement of a towering metropolis, booking everything with Travelocity saves you time, money and hassle. No need to scour through hundreds of different websites for the best deal — our Price Match Guarantee ensures you'll always get the lowest possible price, and our professional customer service experts are available 24/7.

Can I save on my Upstate South Carolina car rental if I book it with hotels and flights?

Definitely. And our Upstate South Carolina vacation packages will help you do it. In just a few clicks you can save cash as well as time by bundling your bookings. Collect the keys to your rental car then chart your own course. Looking for things to do? Add some activities or experiences to your package and make savings on those too.

Which airport is best for Upstate South Carolina?

If you're flying into Upstate South Carolina, you'll probably be touching down at Greenville-Spartanburg Intl. Airport (GSP) or Asheville Regional Airport (AVL).

What is there to do in Upstate South Carolina?

Upstate South Carolina boasts hidden gems around every turn, but make sure you see Clemson University and Lake Keowee while you're in town. These attractions shouldn't be missed.